"The Flintstone Flyer"

September 30, 1960

"The Flintstone Flyer"

"The Flintstones" was television's first prime-time animated series. On September 30, 1960, "The Flintstone Flyer" aired and was the first of 166 original episodes which ran from 1960-1966.

http://i-flintstones.tripod.com/info.htm